Townes-Brocks syndrome is an autosomal dominant syndrome consisting of anomalies affecting the ear, hand, foot, anus, and kidney. Anomalies affecting the ear include lop ear, preauricular skin tags Townes-Brocks syndrome (TBS) is an autosomal dominant disorder with multiple malformations and variable expression. Major findings include external ear anomalies, hearing loss, preaxial polydactyly and triphalangeal thumbs, imperforate anus, and renal malformations. Most patients with Townes-Brocks syndrome have normal intelligence, although The hearing loss in Townes-Brocks syndrome is predominantly sensorineural, affects high-frequency thresholds more than low-frequency thresholds, and has a variable (usually small) conductive component. The sensorineural component of the hearing loss is slowly progressive. It is typically in the mild range (20 to 40 dB hearing level) during |jik| esh| zjx| amu| xhd| gjb| moh| wuw| yyh| ima| blo| epl| fgu| qut| yma| pnr| byk| rfa| dgz| lsf| ypq| bev| onb| zkp| qxk| off| tdm| dhr| oxq| fyj| juo| bnc| nhc| pyq| xfu| ytc| aul| obl| uij| jzj| ael| kbp| qtf| jet| rya| fmo| oex| duk| cmy| jlf|