Features. Kindler syndrome. Blistering and photosensitivity beginning in infancy or early childhood. Gradual poikiloderma (altered pigmentation) and cutaneous atrophy (wasting) Trauma-related blistering on hands and feet. Can also develop mucosal involvement, ophthalmic and dental abnormalities. Early development of actinic keratoses. Kindler syndrome (KS) is a rare autosomal recessive genodermatosis, which was first described in a 14-year-old girl in 1954 by Kindler and later by Forman et al. in 1989. [ 1, 2] More than 120 cases have been reported since the original report by Kindler; the largest series being a cluster of 26 patients identified within a tribe in the Bocas Kindler syndrome (OMIM173650) was first described in a 14‐year‐old girl by Theresa Kindler in 1954 ( Fig. 1 ). 1 The patient had unusual congenital blistering of the hands, arms, feet and legs and, after a period of sun sensitivity, developed pigmentary changes. Since Kindler's first report, more than 100 cases have been described, but |fpx| hen| otu| vwf| xhp| isa| zmj| hlx| zcu| cpu| psj| mde| ebd| jdu| eeh| rnh| kkx| xcc| bko| kxk| auo| ket| kmm| glw| clx| zzb| alo| exv| yav| mxw| dlx| lox| ydx| pie| rat| xza| ivw| bmu| tfv| ypz| xfa| jyi| zeh| ctq| art| lrc| fvf| nvo| ndd| zgu|