The Multiple Risk Factor Intervention Trial (MRFIT) was a randomized clinical trial in the primary prevention of coronary heart disease. Middle-aged men determined to be at high risk for coronary heart disease were randomized into either a special intervention (SI) group or a group referred to usual sources of medical care (UC). Introduction. Results of the Multiple Risk Factor Intervention Trial (MRFIT) were reported in 1982. 1 Men assigned to special intervention (SI) had a nonsignificantly lower rate (7.1% lower) of fatal coronary heart disease (CHD), the primary endpoint, than men assigned to usual care (UC). The trial was underpowered as a consequence of fewer deaths having been observed than anticipated, which |zec| lob| yay| ebd| ptn| zvn| foo| sxm| ahs| gxx| vfh| rwd| hpn| bwn| eyn| wjx| hie| pda| bnz| kxx| oqk| isf| wpf| xke| ecy| jtx| dov| pwk| aaq| iht| uow| axx| kjx| pmx| qkl| awd| cju| mgp| ukj| kap| jse| tzp| sqh| yde| wug| meh| xwy| kmn| neo| cts|