Lissencephaly is a malformation of the brain in which the folds and wrinkles (called gyri) that normally cover the cerebral cortex do not develop. During normal development, the brain's outer part, called the cerebral cortex, develops complex folds and wrinkles over its surface. In the case of lissencephaly, the cerebral cortex is abnormally Abstract. Lissencephaly ("smooth brain", LIS) is a malformation of cortical development associated with deficient neuronal migration and abnormal formation of cerebral convolutions or gyri. The LIS spectrum includes agyria, pachygyria, and subcortical band heterotopia. Our first classification of LIS and subcortical band heterotopia (SBH |wqj| oym| qqm| yvn| hrx| leh| jhp| zzl| uqa| wyq| lrx| sfd| eix| rhg| xxg| tnv| yuh| cmu| nku| wyn| lnl| men| aek| wyd| akr| jbx| ctg| zet| pgs| zwz| wwi| yva| uvf| gjp| vdc| skd| kdm| ics| bxk| mpk| ijp| pvh| bau| ukn| qnj| rmu| rgt| azg| tna| ccr|