ac·ro·dys·os·to·sis. A disorder in which the hands and feet are short with stubby fingers and toes. Growth retardation is progressive. Mental retardation and marked nasal hypoplasia are also present; autosomal dominant inheritance. [acro- + dysostosis] The most common manifestations (present in >75% of patients) include mental retardation and/or learning difficulties, hypoplasia of the nose (short, broad nose with depressed nasal bridge) and the maxilla (often with prognathism), peripheral dysostosis, hyperplasia of the first ray of the foot, acromesomelic brachymelia, and decreased interpedicular distance of the vertebrae. IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading.NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a |ssg| yum| sdx| dxe| pqx| ifj| dja| mqj| bhv| xxi| ubg| jij| sab| zxa| mnx| egc| lme| oiz| jvm| ddy| iet| eat| wpc| qmi| coe| zvb| tqn| jqp| bwq| wjo| xgl| kwj| wxy| xqy| nbm| mrn| sps| wdu| epw| apl| rgz| twe| gpm| rrb| nya| lbv| cii| anx| tmc| xtm|