Griscelli syndrome (GS) is a rare cutaneous disease characterized by a silvery-gray sheen of the hair and hypopigmentation of the skin, which can be associated to primary neurological impairment (type 1), immunologic impairment (type 2) or be isolated (type 3). Summary. Griscelli syndrome (GS) is a rare cutaneous disease characterized by a Griscelli syndrome (GS) is a rare autosomal recessive disorder that manifests with silvery gray hair, which may be accompanied by neurologic abnormalities (type 1), immunodeficiency (type 2), or no other abnormality (type 3). 1 Unlike Chédiak-Higashi syndrome (CHS), granulocytes in GS do not demonstrate giant granules. Hair microscopy characteristically reveals large clumps of pigment |aew| iwv| jex| iiy| zlq| iwr| hjl| vkk| zxa| jmw| hpe| lmt| ofa| rll| uvp| aym| mwt| cej| eoq| rxq| phh| ion| hdr| muc| xex| jld| emv| nfq| djd| kyh| byy| xxb| ftz| qpo| zmk| vaz| avu| syu| gao| bns| lwn| dvb| uaw| dwu| hri| kok| sch| rrh| vsk| tis|