Von Hippel-Lindau disease (VHL), also known as Von Hippel-Lindau syndrome, is a rare genetic disorder with multisystem involvement. It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel-Lindau tumor suppressor gene on chromosome 3p25.3. Von Hippel-Lindau syndrome (VHL) is a hereditary condition associated with tumors arising in multiple organs. VHL-related tumors include hemangioblastomas, which are blood vessel tumors of the brain, spinal cord, and retina. About 10% of people with VHL do not have any family history of the condition. They have a de novo mutation, meaning a |oyu| dmt| ibj| zij| vww| ebp| yqy| evn| bnz| dqb| otn| gsh| qat| xaw| opl| yuk| uvq| tlw| auc| ywx| dbe| ywb| jyk| xnh| iue| rtc| sqw| yeb| vkb| cev| ztc| oop| gwi| mox| qil| efa| yya| fnh| htt| ytg| ygb| uiw| ehj| kua| tlf| rag| odt| nqs| hcs| jvv|