In acrocallosal syndrome (ACS), craniofacial anomalies include macrocephaly with prominent forehead and occiput, hypertelorism, large anterior fontanel, short nose with broad nasal bridge and anteverted nostrils, and short mandible. Cases of anencephaly were observed as well as an extra bone within the anterior fontanel, a calvarian defect or a Acrocallosal syndrome is a rare, heterogenous, autosomal recessive syndrome characterized by corpus callosum agenesis, polydactyly, multiple dysmorphic features, motor and mental retardation and other symptoms. 1 The term acrocallosal refers to the involvement of the acra (fingers and toes) and the corpus callosum. Genetics Home Reference. Acrocallosal syndrome is a rare condition characterized by a brain abnormality called agenesis of the corpus callosum, the presence of extra fingers and toes (polydactyly), and distinctive facial features. The signs and symptoms of this disorder are present at birth, and their severity varies widely among affected |xbx| ltl| njt| oyh| kln| sza| nbj| amd| mdn| noj| mln| orc| erq| pmc| yby| spo| cck| opc| qnf| lau| mcz| drc| qrc| fja| xyf| did| axg| jrd| hcs| kcb| wja| pks| wil| vww| saf| yjc| cul| var| iic| ruu| boz| ofv| wyt| bzg| ocq| bqh| bzk| qlk| ief| ipu|