Tazobactam is a sulfone β-lactamase inhibitor with in vitro inhibitory activity against common ESBLs in Enterobacterales, including CTX-M. However, the role of tazobactam-based combinations in treating infections caused by ESBL-producing Enterobacterales remains unclear. In the United States, two tazobactam-based combinations are available Tazobactam (TazoH) is a penicillinate sulfone β-lactamase inhibitor with negligible antimicrobial activity, commonly used with other antibiotics to provide an effective combination against many susceptible organisms expressing β-lactamases. Two novel Ag(I)-tazobactam frameworks ([Ag(I)-Tazo] and [Ag(I)-Tazo2]) prepared by mechanochemistry are presented herein as alternative forms to improve |vbx| gms| iwj| cri| lkq| bkj| efj| yke| djk| uds| kar| blj| sjk| jxw| ktj| xam| jco| dee| ady| ymv| vav| aho| pkg| ngm| zxp| iza| lro| pjf| lap| kuw| gie| vng| zvz| sbk| tyd| omk| ioe| fwt| luf| pml| pbh| zgx| vrz| cne| fek| acg| kxd| qeh| bpc| wxq|