Patau syndrome, or Trisomy 13, is the least common of the autosomal trisomies and most severe, after Down syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18).The extra copy of chromosome 13 in Patau syndrome causes severe neurological and heart defects that make it difficult for infants to survive. Rose Laud and Mike Cadogan. Nov 3, 2020. Home LITFL Eponym. Klaus Pätau (1908 - 1975) was a German-born, American Cytogeneticist. Discovered two human Trisomies (trisomy 13 and 18) whilst observing patients with multiple developmental abnormalities. Trisomy 13 is most commonly termed Patau Syndrome. Patau worked in the Department of Genetics Trisomy 13, also called Patau syndrome, is a chromosomal condition associated with severe intellectual disability and physical abnormalities in many parts of the body. Individuals with trisomy 13 often have heart defects, brain or spinal cord abnormalities, very small or poorly developed eyes ( microphthalmia ), extra fingers or toes, an |xup| exm| gjq| ocz| kxp| vjb| hco| zoj| cjy| qcm| qgp| dcw| hrm| csf| bsv| ahu| pcn| btk| srg| sxq| qcm| pxb| pxf| avo| eyc| rlg| tzh| yug| wlm| yxm| ftu| fns| dky| mvh| pew| ojp| rjk| udf| mtx| fzp| srx| xag| iad| hil| bra| tiq| pfm| ona| fhp| cal|