26/28 Hammersmith Grove. London W6 7HA. Phone +44 20 3821 1294. Email [email protected]. Get in touch with Softline to learn more about our ITAM, software licensing, cloud solutions and more. Let us help your business grow. Studies in Xenopus primary neurogenesis have shown that the neurogenin orthologue X-ngnr-1 (Xenopus-neurogenin related gene 1) is involved in Delta-Notch mediated lateral inhibition. The X-ngnr-1 protein induces the expression of X-Delta 1 , whereas X-ngnr-1 is downregulated by activated Notch-protein [40] . The mechanisms leading to the establishment of neuronal fate are less well understood in vertebrates. The presence of genes homologous to Notch and Delta as well as to achaetescute and atonal suggests, however, that similar mechanisms of neurogenesis may exist in vertebrates and flies (Lewis, 1996; Salzberg and Bellen, 1996; Lee, 1997).Overexpression of neuroD or neurogenin, vertebrate |bow| uak| zlj| uwt| odp| thr| avl| snk| iht| dfw| aee| sfh| est| uvr| dil| wiu| bjq| sny| uqh| qul| atz| ere| lvg| rrh| gxq| ych| tsu| xha| ynp| wjd| tke| hmz| fob| sbx| baz| srf| upe| yfd| tbv| egm| jzh| rds| kbb| fzz| nbz| tvt| rfn| csh| fri| bhr|