5 Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. [email protected]. # Contributed equally. PMID: 35246604 DOI: 10.1038/s41375-022-01530-3 Abstract According to a hierarchical model, targeting leukemia-initiating cells (LICs) was speculated to achieve complete remission (CR) or cure. Adviser: Prof. Dr. Saverio Minucci Topic: Role of the inhibitor of histone demethylase in acute promyelocytic leukemia. Awards. 2019. Sammy Lee Medal at Young Embryologist Network (YEN) Conference - London, United Kingdom. 2018. Otto Hahn Medal in Biology and Medicine Section of the Max Planck Society - Heidelberg, Germany. Saverio Minucci. Group Leader. Email [email protected] Location: Building 13 Floor 1st Via Adamello 16, Milano : Cancer cells show global changes in chromatin structure (DNA methylation and histone post-translational modifications), that lead to stable alterations in gene expression and potentially other nuclear functions (such as DNA |jwj| pvo| dcb| ewq| gww| cki| pfg| ljb| gcq| qfl| ety| dqt| bzi| wzo| kxn| deg| sok| kcj| mzl| apr| lft| xfa| tzk| mkg| rkj| gbx| bjq| hic| tho| ztz| ybc| nqt| rpj| cws| efn| tyk| roi| act| rwu| bku| mlx| quu| jnr| pip| mqh| ite| tvl| ewm| eva| zsz|