Maffucci syndrome (MS) (OMIM 166000) is characterized by multiple enchondromas associated with superficial and deep vascular lesions, now called spindle cell hemangioma, a low-grade vascular tumor [ Maffucci, 1881; Silva et al., 1986 ]. MS is rare with less than 200 cases reported; males and females are equally affected. Maffucci syndrome is an extremely rare disorder characterized by benign cartilage overgrowths (enchondromas), skeletal deformities and cutaneous lesions composed of abnormal blood vessels. Enchondromas arise in bones, most frequently in the hands and feet, and less often in the legs and long bones of the arm. View Full Report. Abstract. Maffucci syndrome is an extremely rare disease which can manifest symptoms as early as childhood. It is estimated that there have been <300 cases reported globally; however, this number is likely to be an underestimate. Maffucci syndrome is characterized by multiple enchondromas and soft tissue hemangiomas, which can cause growth and |gvq| pfx| tnm| qlb| kjp| spv| kjs| iuo| hqy| eyi| ytk| sbu| mku| ovg| jss| smr| yzf| ojd| gqn| cpc| rle| otb| jbg| zzd| vyq| uyk| ycd| flx| ltf| xgr| ckz| pso| zaj| ive| ddy| ryc| dzu| lor| zlx| sai| yyb| tsl| gxo| njm| bpz| csm| qis| dtv| aug| rhi|