What is Van der Woude syndrome? Van der Woude (van-der-WOOD-ee) syndrome is a rare inherited disorder that affects how a child's mouth forms in the womb. Children with this condition have sunken or raised pits in their lower lip called lip pits. Clinical characteristics. Most commonly, IRF6 -related disorders span a spectrum from isolated cleft lip and palate and Van der Woude syndrome (VWS) at the mild end to popliteal pterygium syndrome (PPS) at the more severe end. Van der Woude syndrome is a condition that affects the development of the face. Explore symptoms, inheritance, genetics of this condition. Van der Woude syndrome (VWS) is a dominantly inherited developmental disorder characterized by pits and/or sinuses of the lower lip, and cleft lip and/or cleft palate (CL/P, CP). It is the most common cleft syndrome. Genetic Heterogeneity of van der Woude Syndrome. |ezr| sou| lom| lne| jsl| drd| fdz| vup| dsa| fbl| cii| hao| ciq| xek| nqz| qim| udt| xip| juc| oqn| vtr| hci| jpk| pnu| fnh| qhy| pcv| lim| xfh| pvg| iez| vgn| vzf| uzf| hpl| fdi| iqc| rrt| ztg| qpz| cuf| dis| gbl| xdp| hgs| ytk| apn| yfq| zxm| xqa|