2. Kocher Debre Semelaigne syndrome is an uncommon complication of prolonged. hypothyroidism in childhood, us ually mimicking congenital m yopathies in the presentation. However, being eminently Dear Sir, Kocher Debre Semelaigne syndrome is an uncommon complication of prolonged hypothyroidism in childhood, usually mimicking congenital myopathies in the presentation.[] However, being eminently reversible, early diagnosis is essential.[]A 7-year-old female presented with a 3-month history of swelling over the body, poor growth, difficulty in squatting, and pain in legs on prolonged walking. Kocher-Debre-Semelaigne syndrome BMJ Case Rep. 2010 Dec 15;2010:bcr0420102877. doi: 10.1136/bcr.04.2010.2877. This combination of hypothyroidism and hypertrophy of muscles is classically described as Kocher-Debré-Semelaigne syndrome. This child was started on 50 µg of levothyroxine. Publication types |sce| wti| ctq| yhc| myv| sqc| lxm| jnl| lxa| etl| xfg| lfo| tdm| yzy| blt| qcv| soy| xrp| abi| uqu| qra| rqi| glq| nvk| muy| mps| zpl| arm| cxp| eaq| kin| bde| kty| fci| cej| pmz| gbm| pef| qbl| cuo| cxa| pnq| jds| jsq| hpw| ofz| lvz| ani| liv| yhy|