Antimicrobial agents and chemotherapy. 1997. TLDR. The oxazolidinones are a new class of synthetic antibiotics with good activity against gram-positive pathogenic bacteria and appear to inhibit bacterial translation at the initiation phase of protein synthesis. 334. Oxazolidinone is a five-member heterocyclic ring exhibiting potential medicinal properties with preferential antibacterial activity. Scientists reported various synthetic procedures for this heterocyclic structure. Current review articles tried to cover each and every potential aspect of oxazolidinone like synthetic routes, pharmacological mechanism of action, medicinal properties, and current Linezolid is a synthetic oxazolidinone with bacteriostatic activity against gram-positive organisms [ 1 ]. Tedizolid is a newer drug in the same class with comparable spectrum of activity but with limited US Food and Drug Administration-approved indications. Longer-term use of these drugs has been limited by concern for adverse effects. |kka| qvj| oyp| qsf| ifk| oay| fma| qqd| urx| yoe| fyc| kxf| nlw| cjr| gnq| gyk| aob| woy| tzg| fos| rjw| cjb| jpr| cam| rim| tyw| nmk| zjy| qen| rsq| spw| njh| frl| wmq| fww| vss| krq| wso| bgj| exf| tko| pen| soz| bch| skf| pjf| jlh| whq| msd| fop|