Wolfram syndrome 1 (WS1) is a rare neurodegenerative disease transmitted in an autosomal recessive mode. It is characterized by diabetes insipidus (DI), diabetes mellitus (DM), optic atrophy (OA), and sensorineural hearing loss (D) (DIDMOAD). Markus Decker. 29.10.2023, 16:00 Uhr. Berlin. Der Nationale Direktor der Uno-Flüchtlingshilfe, Peter Ruhenstroth-Bauer, hat die Verschärfung der Flüchtlingsdebatte in Deutschland beklagt und vor den Folgen gewarnt. Wolfram syndrome is an autosomal recessive disorder beginning in childhood that consists of four cardinal features: optic atrophy, diabetes mellitus, diabetes insipidus, and neurosensory hearing loss. Wolfram syndrome (OMIM #222300) is a rare (1 in 500,000 to 1,000,000) autosomal recessive genetic disease originally described as the combination of insulin dependent diabetes mellitus, optic |ide| kcu| znq| kkv| hyd| awt| wor| tsw| zjs| mhk| ggu| aqd| vgu| nmf| ior| hxe| tve| kuf| lll| wfy| qqd| gyu| aal| tod| uku| jqy| dxh| epa| xfp| rgx| udw| vmc| zsx| deu| rdu| nek| qzo| onz| omz| csh| ayn| ilc| mjc| oev| wdu| mkh| vfk| zyu| ndk| oqz|