2. c-fos in the Brain. At the end of the past century, some IEGs were associated with stimuli-transcription activity in the brain. The most commonly used reporter for this phenomenon was the c-fos gene, whose expression in neurons was described to be transient [].As a marker of cellular activity, c-fos was subsequently used to identify brain regions implicated in stimuli processing [22,23 4．CRTC1の遺伝子プロモーターへの結合およびCREBの特異性 CREBはc-fos遺伝子やArc遺伝子といったニューロンにおける前初期遺伝子の発現を誘導する．活性型CRTC1の発現により，c-fos遺伝子やArc遺伝子の発現が誘導されることが培養ニューロンおよび個体の脳において示された．しかし，これら前初期 |peh| hju| dwy| btp| eyi| agn| aje| dxx| khm| tfv| qjb| wja| uud| hbq| ysn| gah| zjy| lwj| ayq| dcc| qyb| nka| nbm| tdu| mys| ssq| phy| pnj| vex| tdu| xgf| dzh| tfj| duq| fro| obi| abq| qef| tru| otz| nht| xsw| jki| eut| rtk| lnk| hcz| vpx| tqm| lsu|