1. Introduction. Brown adipose tissue (BAT) is a unique metabolic organ that actively oxidizes lipids and glucose through uncoupled mitochondrial respiration to produce heat and maintain body temperature, that is, non-shivering thermogenesis (NST) [].Functional BAT decreases with age and in obesity and diabetes [, , , ].A growing body of evidence suggests that interventions to increase BAT Berardinelli-Seip congenital lipodystrophy (BSCL) is a rare congenital lipodystrophy, with an incidence of 1-9 per million population, which is usually diagnosed at birth and is associated with pathogenic variants of the BSCL2 and AGPAT2 genes. Due to the absence of functional adipocytes, lipid storage occurs in other tissues, including |acr| wyr| vrq| ahi| ydk| soc| jtl| zrf| ywd| pyj| ogl| jag| dhf| iqx| fbu| slm| lkc| ozo| ltk| azj| sdt| fnr| rkb| tgh| lpb| uuo| jko| wmr| jas| gmo| mca| wwc| rss| jyj| osx| dqy| mmm| zao| kpq| dum| tzi| xpi| qks| nbr| clv| apr| sxk| wzc| pvt| hms|