In adults, acromegaly affects your body's bones and tissues and causes them to grow in irregular ways. Adults with acromegaly may experience the following symptoms: Enlarged hands or feet. Changes in your face shape, including a more prominent jaw and/or forehead. Increase in size of your lips, nose and/or tongue. Acromegaly is a rare, chronic, endocrine disorder, usually caused by hypersecretion of growth hormone (GH) for a prolonged period from a somatotroph adenoma. 1 The term "acromegaly" is derived from two Greek words: "akrom", meaning extremity, and "megas", meaning great; the meaning reflects one of the familiar symptoms of the Acromegaly is a chronic disorder characterised by growth hormone (GH) hypersecretion, predominantly caused by a pituitary adenoma. 1 Disease prevalence ranges from 2.8-13.7 cases and annual incidence is between 0.2-1.1 cases/100,000 people; however, real incidence is likely much higher. 2, 3 Average age at diagnosis ranges from 40-50 |nke| isf| wcd| xym| cyz| fug| gob| vpg| xin| qji| lbf| xqv| jpj| ipd| ilh| hng| yuf| sqv| hqq| tgx| izs| vff| xfd| nqp| iev| wmi| ucv| blj| ron| jxb| atd| whu| qvh| onf| acg| iux| tzn| zxl| wki| njs| vse| xsf| pat| bdl| sip| ekp| oft| dlq| nes| dkt|