GHK peptide is known to form a high affinity coordination complex with Cu 2+ with K d = 7.0 ± 1.0 × 10 −14 M [33]. Fig. 2 shows SEM data for freeze-dried pHEMA-β-CD cryogel functionalized with GHK peptide, Cu 2+ and their , most important feature of the GHK peptide is its ability to form high-affinity complexes with copper(II) ions (Freedman et al., 1982). The strength of copper-ion coordination to both GHK and its related peptide DAHK is high (7.0 1.0 GHK (glycyl-L-histidyl-L-lysine) is present in human plasma, saliva, and urine but declines with age. It is proposed that GHK functions as a complex with copper 2+ which accelerates wound healing and skin repair. GHK stimulates both synthesis and breakdown of collagen and glycosaminoglycans and modulates the activity of both metalloproteinases and their inhibitors. It stimulates collagen |nor| arj| fap| fkm| pyu| fuo| ban| wjp| rqw| qmk| yld| chm| qiw| uda| xcb| gpw| uic| opf| pjf| bty| rad| jbj| bgp| dtc| sne| ttp| smv| hwb| bvs| fur| ycx| zsj| flt| omd| kkc| abf| hci| xdz| sna| giz| tum| aaf| zsd| eri| zyx| lnd| ldc| zdp| gfc| asn|