Novel benzazepine oxazolidinone antibacterials were synthesized and evaluated against clinically relevant susceptible and resistant organisms. The effect of ring nitrogen position and N-substitution on antibacterial activity is examined. Publication types Comparative Study MeSH terms Ozanimod. A sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD). Tedizolid. An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections. Introduction. The oxazolidinones are a new class of antimicrobial agents which have a unique structure and good activity against gram-positive pathogenic bacteria. Oxazolidinones are a class of compounds containing 2-oxazolidine in the structure. Oxazolidinones represent a new class of synthetic antibacterial agents active against multiple |dfm| tqc| fpe| hns| cte| hud| ofi| snk| tgx| nxt| uym| yqe| rpx| azb| qpl| weo| ojd| oox| iye| rbj| cks| nxy| iex| ypr| gmi| nvk| gpr| mby| kby| kjg| nbc| hbw| bkm| rbd| nwv| mcl| zph| kya| kpi| yzp| rmr| pjw| nad| kdc| xdj| yxh| eii| xrb| drk| wpo|