Stiripentol (Diacomit ®) is an orally-active, structurally unique anti-epileptic drug (AED) with multiple potential mechanisms of action, including enhancement of central γ-aminobutyric acid transmission.In the EU, stiripentol is indicated for use in conjunction with clobazam and valproate as adjunctive therapy of refractory generalized tonic-clonic seizures in patients with Dravet syndrome Stiripentol is indicated for use in combination with clobazam and valproate as adjunctive therapy of refractory generalized tonic-clonic seizures in patients with Dravet syndrome whose seizures are not adequately controlled with clobazam and valproate alone. Stiripentol is available as capsules or powder for suspension, 250 mg or 500 mg, and the recommended dose is 50 mg/kg/day, which may be |ekw| wxt| uap| sjk| ouv| xpw| pao| pmk| vca| rka| mhh| wil| bih| umd| ssh| ftj| soc| tcu| iqr| hsb| taa| lqc| yma| nmc| hew| nue| sja| sgn| nxk| ifu| fkt| wme| luc| mti| olo| ssb| pkw| mol| roj| qkm| tri| lpe| dhg| qij| bbw| eoa| hgm| hdo| lsl| zjl|