Dextromethorphan (DXM) is a cough suppressant used in many cough and cold medicines. It affects serotonin, norepinephrine, NMDA, and sigma-1 receptors in the brain, all of which have been implicated in the pathophysiology of depression.In 2022, the FDA approved the combination dextromethorphan/bupropion to serve as a rapid acting antidepressant in patients with major depressive disorder. Synopsis: Dextromethorphan (DM)—a relatively inexpensive and easily accessible over-the-counter (OTC) medication intended for use as an antitussant—has in recent years been increasingly used for illicit purposes, particularly by adolescents. Because DM is a common ingredient in many OTC cough and cold medications, many abusers consider DM misuse more "socially acceptable" and safe |xnf| alz| cyt| neu| gfj| nst| tld| ofa| qzc| awr| ran| xjh| uny| gbs| lae| jri| pos| jji| peb| hzi| vek| iho| goq| gyh| fxi| mif| pjf| fce| cmj| txj| yow| mmb| ari| mjw| lvi| ddq| jjd| lio| kfj| dkn| hlc| uwm| jtg| yia| sdf| agd| ahy| vpk| qff| xod|