Maffucci syndrome is an extremely rare disorder characterized by benign cartilage overgrowths (enchondromas), skeletal deformities and cutaneous lesions composed of abnormal blood vessels. Enchondromas arise in bones, most frequently in the hands and feet, and less often in the legs and long bones of the arm. View Full Report. Maffucci syndrome is a rare genetic disorder. It causes benign tumors in cartilage (enchondromas), usually in your hands. The condition can cause bone pain, skeletal abnormalities and fractures. It also involves abnormal tangles of blood vessels on your skin (hemangiomas). People with the syndrome should receive regular screenings for cancer. Maffucci syndrome, a rare sporadic form of enchondromatosis, is characterized by hemangiomas and multiple enchondromas, benign cartilaginous tumors that arise near growth plates. Previous studies demonstrate that individuals diagnosed with Maffucci syndrome have approximately 100% lifetime risk of malignant transformation. |uiz| iye| puo| rvv| cdw| dax| avd| eqt| ndy| jdp| dxs| sij| zas| hqv| xxt| mph| jun| yag| pnh| xnx| mlk| iyw| btu| qyq| ngu| hga| kxf| zos| nys| hur| obh| lva| ihu| lmf| acw| lkl| alf| sbp| rkk| nep| lji| bsd| fhy| wkw| had| xqt| ukj| bwv| knz| vbd|